PhotoSynLab

Correlation between cell count using flow cytometer (and hemocytometer) and OD750nm values

Intersection point

Linear correlation equation

Correlation coefficient (R)

Hemocytometry

Flow cytometry

H.cytometry

F. cytometry

= 0.00

y = 2E-08x

y = 2E-08x

0,9972

0,9728

≠ 0.00

y = 2E-08x + 0,0024

y = 2E-08x + 0,0047

0,9986

0,9808

The correlation equations are then used to determine the cell number of your cell culture, where x is the cell number in the cell culture, and y is the OD750nm value of that cell culture. The difference between the equations are not significant either the correlation line goes trough the intersection point equal zero, or not. Therefore, both can be used.